You might think antidepressants are a human-only thing — but sometimes our pups are prescribed them, too. And while they can help with certain issues, they’re not usually given for what we think of as “dog depression.”
Are antidepressants used for dog depression?
Not often.
True clinical depression in dogs is rare, and when dogs seem depressed, there’s usually a physical cause behind it — pain, illness or another medical issue that affects their mood.
In these cases, your vet’s job is to figure out what’s really going on and treat the root problem. Once that’s addressed, most dogs bounce back without needing antidepressants at all.
Why a Dog Might Be Prescribed Antidepressants
Even though they’re not typically used to treat depression, antidepressants — especially SSRIs like Prozac — can be incredibly helpful for certain behavioral and medical conditions, including:
- Obsessive-compulsive behaviors
- Separation anxiety
- Generalized anxiety
- Certain types of dog aggression
Vets may also prescribe tricyclic antidepressants for issues like aggression, OCD-type behaviors, separation anxiety, or fears and phobias — including thunderstorm anxiety.
Possible Side Effects
Like any medication, antidepressants can come with side effects. Some of the more common ones include:
- Upset stomach
- Increased excitement
- Increased sleepiness
- Liver changes
There’s also a more serious risk called serotonin syndrome, which happens when too much serotonin builds up in the nervous system. Dogs are actually more sensitive to this than humans are, which is why close monitoring is essential.
If your dog starts antidepressants, your vet will want regular updates so the dose can be adjusted quickly if needed.
The Bottom Line
Behavioral health — in both dogs and humans — is complex. If you think your dog needs help with anxiety, compulsive behaviors or other emotional challenges, talking with a veterinary behaviorist (or having a detailed conversation with your vet) is the best next step.
With the right plan, your pup can feel happier, calmer and more confident.
